Cancer Stem Cell Differentiation In Reverse, Spontaneously
By
Mark Ratner / Email the Author / START-UP April 2011, Vol. 16, No. 4
Science Matters / Word Count: 938 / Article # 2011900080
Executive Summary
Scientists have now shown that both normal and cancerous mammary cells may spontaneously "de-differentiate" into stem cells without any genetic manipulations. This apparently innate cellular plasticity suggests new possibilities for utilizing cultured cells both as a tool in the discovery of cancer therapies that target cancer stem cells and also as an autologous therapy in regenerative medicine.
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